The prostate health index (phi) is a mathematical formula that provides a probability of prostate cancer (PCa) by combining three tests (prostate-specific antigen [PSA], free PSA, and p2PSA) into a single score.
The CUHK Urology team has carried out and published their study on the clinical efficiency of the phi in Asian population in the detection of prostate cancer in patients with PSA blood test level between 4 and 10 ng/mL. (Reference: The Prostate Health Index in predicting initial prostate biopsy outcomes in Asian men with prostate-specific antigen levels of 4-10 ng/mL)
The higher the phi score, the greater the probability of finding prostate cancer disease upon prostate biopsy. The study has shown a lower incidence of prostate cancer in Asian population compared to western population. The appropriate usage of phi score could decrease the number of patients who are selected to undergo a prostate biopsy.